Lenacapavir sodium

Lenacapavir (GS-6207) sodium is a HIV-1 capsid inhibitor. Lenacapavir sodium shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. Lenacapavir sodium displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs).


Cat. No.: EX-A5518A	Purity: >98%

	Chemical structure of Lenacapavir sodium

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	650	In-stock
1g	1065	In-stock
5g	3900	In-stock
10g	6642	get quote
25g	get quote	In-stock
50g	get quote	In-stock

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CAS No.	2283356-12-5
Purity	>98%
Formula	C39H33ClF10N7NaO5S2
Mol Weight	992.28
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Singh K, et al. GS-CA Compounds: First-In-Class HIV-1 Capsid Inhibitors Covering Multiple Grounds. Front Microbiol. 2019 Jun 20;10:1227. [2]. John O Link, et al. Clinical targeting of HIV capsid protein with a long-acting small molecule. Nature. 2020 Jul 1.
CoA	CoA of Lenacapavir sodium

Smiles:	C(F)(F)(F)C=1C=2[C@@]3([C@@](C3)(C(F)(F)C2N(CC(N[C@@H](CC4=CC(F)=CC(F)=C4)C5=C(C=CC(C#CC(S(C)(=O)=O)(C)C)=N5)C6=C7C(C(NS(C)(=O)=O)=NN7CC(F)(F)F)=C(Cl)C=C6)=O)N1)[H])[H].[Na]


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